Principal Investigator

Adam J. Woods, Ph.D.

Associate Professor and Assistant Director

headshot

Dr. Adam J. Woods

Post-Doctoral Fellow, Cognitive Neuroscience, University of Pennsylvania, Philadelphia, PA
PhD, Cognitive Neuroscience, George Washington University, Washington, DC
BS, Psychology, University of Alabama at Birmingham, Birmingham, AL

E-mail:  ajwoods@phhp.ufl.edu 
Phone:  352-294-5842

Full C.V.

Primary Appointment:

Associate Professor, Preeminence Term Professor
Department of Clinical and Health Psychology
College of Public Health and Health Professions
University of Florida

Assistant Director

Center for Cognitive Aging and Memory
McKnight Brain Institute
College of Medicine
University of Florida

Professional Interests

Cognitive Aging: Cognitive function declines as we age. As our thinking and memory skills decline, the rate of functional dependence, mortality, and acute illness requiring hospitalization increases. A variety of methods have been proposed to counteract cognitive aging (e.g., cognitive training). Unfortunately, these techniques have limited degrees of success and transfer to everyday life. My work demonstrates that combining treatments like cognitive training with non-invasive brain stimulation (tDCS, TMS, tACS) facilitates neuroplastic response of brain tissue, improves cognitive abilities (specifically working memory, attention, and speed of processing), and leads to long-term improvement. In combination with modern multimodal neuroimaging and electrophysiology recording, this work not only identifies mechanisms underlying improvement, but also provides information important for further optimizing treatment effectiveness. Dr. Woods is PI of the largest NIH/NIA-funded Phase III tDCS trial, the ACT study. The ACT study investigates benefits of tDCS paired with cognitive training for cognitive and brain function and slowing onset of dementia in older adults.

Methodological Expertise: Non-invasive brain stimulation (transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS)); brain imaging (structural and functional magnetic resonance imaging); magnetic resonance spectroscopy (1H and 31P), human electrophysiology (event-related potentials).

Honors and Awards

2018-2012, Preeminence Term Professor, College of Public Health and Health Professions, University of Florida

2015, Young Investigator Award, NYC Neuromodulation Conference

2014, Elected as Junior Member of the World Academy of Art and Science

2009-2010, Thelma Hunt Research Fellowship, George Washington University

2006-2009, NSF Graduate Research Fellowship, National Science Foundation

2003, John P. Ost Undergraduate Psychology Research Award

Publications

Refereed Publications (by topic)

Neuromodulation

Im J, Jeong H, Bikson M, Woods AJ, Unal G, Oh J, Na S, Park J, Knotkova H, Song I, Cung Y. Effects of 6-month at-home transcranial direct current stimulation on cognition and cerebral glucose metabolism in Alzheimer’s disease. Brain Stimulation. Accepted June 2019.

Nissim N, Nissim N, O’Shea A, Indahlastari A, Telles R, Richards L, Porges E, Cohen R, Woods AJ. Effects of in-scanner bilateral frontal tDCS on functional connectivity of the working memory network in older adults. Frontiers in Aging Neuroscience. Accepted February 2019.

Indahlastari A, Albizu A, Nissim N, Traeger K, O’Shea A, Woods AJMethods to monitor accurate and consistent electrode placements in conventional transcranial electrical stimulation. Brain Stimulation. Accepted October 2018.

Soyata A, Aksu S(&), Woods AJ, Iscen P, Sacar K, Karamursel S. Effects of transcranial direct current stimulation on decision making and cognitive flexibility in gambling disorder. European Archives of Psychiatry and Clinical Neuroscience.Accepted October 2018.

Gedoth N, Esmaeilpour Z, Adair D, Chelette K, Dmochowski D, Woods AJ, Kappenman E, Parra L, Bikson M. Inherent physiological artifacts in EEG during tDCS. NeuroImage. Accepted October 2018.

Ahn H, Suchting R, Woods AJ, Miao H, Green C, Cho R, Choi E, Fillingim R. Bayesian Analysis of the Effect of Transcranial Direct Current Stimulation on Experimental Pain Sensitivity in Older Adults with Knee Osteoarthritis: Randomized Sham-Controlled Pilot Clinical Study. Journal of Pain Research. Accepted August 2018.

Thomas C, Datta A, Woods AJ. Effect of aging on cortical current flow due to transcranial direct current stimulation: considerations for safety. IEEE:EMBC. Accepted April 2018.1-8.

Gomes-Osman J, Indahlastari A, Freid PJ, Rice J, Cabral D, Nissim N, Aksu S, McLaren M, Woods AJ. 2018. Non-invasive brain stimulation: probing intracortical circuits and improving cognition in the aging brain. Frontiers in Aging Neuroscience. 10:177. 

Pope C, Stavrinos D, Vance D, Woods AJ, Bell T, Ball K, Fazeli P. 2018. A pilot investigation on the effects of combination transcranial direct current stimulation and speed of processing cognitive remediation therapy on simulated driving behavior in older adults with HIV. Transportation Research Part F: Traffic Psychology and Behavior.58:1061-1073.

Woods AJ, Cohen R, Marsiske M, Alexander G, Czaja S, Wu S. 2018. Augmenting cognitive training in older adults (The ACT Study): Design and methods of a Phase III tDCS and cognitive training trial. Contemporary Clinical Trials. 65: 19-32

Bikson M, Brunoni AR, Charvet LE, Clark V, Cohen LG, Deng Z, Dmochowski J, Edwards D, Frohlich F, Kappenman E, Lim KO, Loo C, Mantovani A, McMullen D, Parra LC, Pearson M, Richardson JD, Rumsey JM, Pejman S, Sommers D, Unal G, Wassermann EM, Woods AJ, Lizanby H. 2018. Rigor and reproducibility in research with transcranial electrical stimulation: An NIMH-sponsored workshop. Brain Stimulation. 11(3): 465-480

McLaren M, Nissim N, Woods AJ. 2018. The effects of medication use in transcranial direct current stimulation: A brief review. Brain Stimulation. 11(1): 52-58

Bikson M, Adair D, Paneri B, Datta A, Mourdoukoutas A, Fang XH, Wingeier B, Chao D, Alonso-Alonso M, Lee K, Knotkova H, Woods AJ,Hagedorn D, Jeffery D, Giordano J, Tyler WJ. 2018. Limited output transcranial electrical stimulation (LOTES-2017): Engineering principles, regulatory statutes, and industry standards for wellness, over-the-counter, or prescription devices with low risk. Brain Stimulation. 11(1): 134-157

Ahn HC, Woods AJ,Kunik ME, Bhattacharjee A, Chen Z, Choi E, Fillingim R. 2017. Efficacy of Transcranial Direct Current Stimulation over Primary Motor Cortex (anode) and Contralateral Supraorbital area (cathode) on Clinical Pain Severity and Mobility Performance in Persons with Knee Osteoarthritis: An experimenter- and participant-blinded, Randomized, Sham-controlled Pilot Clinical Study. Brain Stimulation.10(5): 902-909.

Fazeli P, Woods AJ, Pope CN, Vance D, Ball KK. 2017. The effect of transcranial direct current stimulation combined with cognitive training on cognitive functioning in older adults with HIV: a pilot study. Applied Neuropsychology Adult. 11: 1-12.

Bikson M, Grossman P, Zannou AL, Kronberg G, Truong D, Boggio P, Brunoni AR, Charvet L, Fregni F, Fritsch B, Gillick B, Hamilton RH, Hampstead BM, Kirton A, Knotkova H, Liebetanz D, Liu A, Loo C, Nitsche MA, Reis J, Richardson JD, Rotenberg A, Turkeltaub PE, Woods AJ. 2017. Response to Letter to the Editor: Safety of transcranial direct current stimulation: Evidence basedupdate 2016. Brain Stimulation.10(5): 986-987.

Szymkowicz SM, McLaren ME, Suryadevara U, Woods AJ.2016. The use of transcranial direct current stimulation (tDCS) in the treatment of neuropsychiatric disorders: A brief review. Psychiatric Annals. 46(11): 642-646

Bikson M, Grossman P, Thomas C, Jiang J, Adnan T, Mourdoukoutas P, Kronberg G, Troung D, Boggio P, Brunoni A, Charvet L, Fregni F, Fritsch B, Gillick B, Hamilton R, Hampstead B, Jankford R, Kirton A, Knotkova H, Liebetanz D, Liu A, Loo C, Nitsche M, Richardson J, Rotenberg A, Turkeltaub P, Woods AJ.2016. Safety of transcranial Direct Current Stimulation (tDCS): evidence based update 2016. Brain Stimulation.9(5): 641-661. 

Woods AJ, Antal A, Bikson M, Boggio PS, Brunoni AR, Celnik P, Cohen LG, Fregni F, Herrmann CS, Kappenman ES, Knotkova H, Liebetanz D, Miniussi C, Miranda PC, Paulus W, Priori A, Reato D, Stagg C, Wenderoth N, Nitsche MA.  2016. A technical guide to tDCS, and related non-invasive brain stimulation tools. Clinical Neurophysiology. 127(2): 1031-1048.

Woods AJ, Bryant V, Sacchetti D, Gervits F, Hamilton R.  2015. Effects of electrode drift in transcranial direct current stimulation. Brain Stimulation. 8(3): 515-519.

Woods AJ, Hamilton RH, Kranjec A, Bikson M, Minhaus P, Yu J, Chatterjee A.  2014. Space, time, and causality in the human brain. NeuroImage. 92: 285-297.

Kessler S, Minhas P, Woods AJ, Rosen A, Bikson M.  2013. Dosage considerations for transcranial direct current stimulation in children: a computational modeling study. PLoS ONE. 8(9): e76112.

Minhas P, Bikson M, Woods AJ, Rosen AR, Kessler SK. 2012. Transcranial direct current stimulation in the pediatric versus adult brain: A computational modeling study. IEEE:EMBC. 2012: 859-862.

Mennemeier MS, Triggs W, Chelette KC, Woods AJ, Kimbrell T, Dornhoffer J.  2009. Sham transcranial magnetic stimulation using electrical stimulation of the scalp. Brain Stimulation. 2(3): 168-173.

Woods AJ, Philbeck JW, Wirtz P.  2013. Hyper-arousal decreases human visual thresholds. PLoS ONE. 8(4): e61415. J

Woods AJ, Mennemeier MS, Garcia-Rill E, Huitt T, Chelette KC, McCullough G, Munn T, Brown G, Kiser TS. 2012. Improvement in arousal, visual neglect, and perception of stimulus intensity following cold pressor stimulation. Neurocase. 18(2): 115-122. 

Woods AJ, Philbeck JW, Chelette KC, Skinner RD, Garcia-Rill E, Mennemeier M. 2011. Cold pressor stimulation diminishes P50 amplitude in normal subjects.  Acta Neurobiologiae Experimentalis.71(3): 348-358.

 

Brain Aging & Cognition

Cohen R, Lyon D, Gullett J, Starkweather A, Porges E, Woods AJ, Jackson-Cook C, Lynch-Kelly D. Cytokine-associated fatigue prior to, during and post-chemotherapy for breast cancer. Journal of Neuroimmunology. Accepted June 2019.

 Fernando H, Cohen R, Friedman J, Gullett J(p), Friedman J, Ayzengart A, Porges E, Woods AJ, Gunstad J, Ochoa C, Cusi K, Gonzalez-Louis R, Donahoo W. Neurocognitive deficits in a Class II and Class III obesity cohort: contributions of type-2 diabetes and other medical comorbidities. ObesityAccepted April 2019.

Mikkelsen M, Rimbault D, Barker P, Bhattacharyya P, Brix M, Buur P, Cecil K, Chan K Chen D, Craven A, Cuypers K, Dacko M, Duncan N, Dydak U, Edmondson D, Ende G, Ersland L, Forbes M, Gao F, Greenhouse I, Harris A, He N, Heba S, Hoggard N, Hsu T, Jansen J, Kangarlu A, Lange T, Lebel M, Li Y, Lin C, Liou J, Lirng J, Liu f, Long J, Ma R, Maes C, Moreno-Ortega M, Murray S, Noah S, Noeske R, Noseworthy M, Oeltzschner G, Porges E, Prisciandaro J, Puts N, Roberts T, Sack M, Sailasuta N, Saleh M, Schallmo M, Simard N, Stoffers D, Swinnen S, Tegenthoff M, Truong P, Wang G, Wilkinson I, Wittsack H, Woods AJ, Xu H, Yan F, Zhang C, Zipunnikov V, Zöllner H, Edden R. Big GABA II: Water-Referenced Edited MR Spectroscopy at 25 Research Sites. Neuroimage. Accepted February 2019.

Cruz-Almeida Y, Fillingim R, Riley J, Woods AJ, Porges E, Cohen R, Cole J. Chronic pain is associated with a brain aging biomarker in community-dwelling older adults. Pain. Accepted December 2018. 

Cohen R, Gullet J, Porges E, Woods AJ, Bryant V, Mcadams M, Tashima K, Cook R, Bryant K, Monnig M, Kahler C, Monti P. Heavy alcohol use and age effects on HIV-associated neurocognitive function. Alcoholism: Clinical and Experimental Research. Accepted October 2018.

O’Shea D, Langer K, Woods AJ, Porges E, Williamson J, O’Shea A, Cohen R. Educational attainment moderates the association between hippocampal volumes and memory performance in healthy older adults. Frontiers in Aging Neuroscience. Accepted October 2018.

Wanigatunga A, Gill T, Marsh A, Hsu F, Yaghjyan L, Woods AJ, Glynn N, King A, Newton R, Fielding R, Pahor M, Manini T. Effect of hospitalizations on physical activity patterns in mobility-limited older adults. Journal of the American Geriatric Society. Accepted September 2018.

O’Shea D, Fieo R, Woods AJ, Williamson J, Porges EC, Cohen R. 2018. Discrepancies between crystallized and fluid ability are associated with frequency of social and physical engagement in community dwelling adults. Journal of Clinical and Experimental Neuropsychology. 23:1-8.

Mankowski R, Leeuwenbergh C, Manini T, Woods AJ, Anton SD. 2018. Effects of fermented papaya preparation (FPP) on safety outcomes in older adults – A short report of a placebo-controlled clinical trial. Journal of Frailty & Aging. 7(2): 142-146.

Gullett J, Lamb D, Porges E, Woods AJ, Rieke J, Thompson P, Jahanshad N, Nir T, Tashima K, Cohen R. 2018. The impact of alcohol use on frontal white matter in HIV. Alcoholism: Clinical and Experimental Research. 42(9):164-1649.

Cohen R, Siegel S, Porges E, Tashima K, Woods AJ, Ding MZ. 2018. Neural response to working memory demand predicts neurocognitive deficits in HIV. Journal of NeuroVirology. 24:291-304. 

Szymkowicz SM, Dotson VM, McLaren M, De Witt L, O’Shea D, Talty FT, O’Shea A, Porges EC, Cohen RA, Woods AJ.2017. Precuneus abnormalities in middle-aged to older adults with depressive symptoms: An analysis of BDI-II symptom dimensions. Psychiatry Research: Neuroimaging. 268: 9-14.

Rani A, O’Shea A, Ianov L, Cohen R, Woods AJ, Foster TC. 2017. miRNA in circulating microvesicles as biomarkers for age-related cognitive decline. Frontiers in Aging Neuroscience. 9: 323.

Porges EC, Woods AJ, Lamb DG, Williamson JB, Cohen R, Edden RA, Harris A. 2017. Impact of tissue correction strategy on GABA-Edited MRS findings. NeuroImage. 162: 249-256.

Porges EC, Woods AJ, Edden R, Harris A, Chen H, Garcia A, Lamb D, Williamson JW, Cohen RA. 2017. Frontal GABA concentrations are associated with cognitive performance in older adults. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2: 38-44.

Nissim N, O’Shea A, Bryant V, Porges E, Cohen R, Woods AJ.2017. Frontal structural neural correlates of working memory performance in older adults. Frontiers in Aging Neuroscience. 8: 328.

Seider T, Fieo R, O’Shea A, Porges EC, Woods AJ,Cohen RA. 2016. Cognitively engaging activity is associated with greater cortical and subcortical volume. Frontiers in Aging Neuroscience. 8: 94.

O’Shea A, Cohen RA, Porges EC, Nissim N, Woods AJ.2016. Cognitive aging and the hippocampus in older adults. Frontiers in Aging Neuroscience. 8: 289.

Woods AJ, Porges EC, Bryant V, Seider T, Gongvatana A, Kahler CW, de la Monte S, Monti PM, Cohen RA. 2016. Current heavy alcohol consumption is associated with greater cognitive impairment in older adults. Alcoholism: Clinical and Experimental Research. 40: 2435-2444.

Chen H, Zhao B, Cao G, Porges EC, O’Shea A, Woods AJ, Cohen R. 2016. Statistical approaches for the study of cognitive and brain aging. Frontiers in Aging Neuroscience. 8: 176.

Dotson VM, Szymkowicz SM, Sozda CN, Kirton JW, Green ML, O’Shea A, McLaren ME, Anton SD, Manini TM, Woods AJ.  2016. Age differences in prefrontal surface area and thickness in middle aged to older adults. Frontiers in Aging Neuroscience. 7: 250.

Seider TR, Gongvatana A, Woods AJ, Chen H, Porges EC, Cummings T, Correia S, Tashima K, Cohen RA. 2015. Age exacerbates HIV-associated white matter abnormalities. Journal of Neurovirology. 22(2): 201-212.

Anton S, Woods AJ, Ashizawa T, Barb D, Buford T, Carter C, Clark D, Cohen R, Corbett D, Cruz-Almeida Y, Dotson V, Ebner N, Efron P, Fillingim R, Foster T, Gundermann D, Joseph A, Karabetian C, Leeuwenburgh C, Manini T, Mariske M, Mankowski R, Mutchie H, Perri M, Ranka S, Rashidi P, Sandesara B, Scarpace P, Sibille K, Solberg L, Someya S, Uphold C, Wohlgermuth S, Wu S, Pahor M. 2015. Successful aging: Advancing the science of physical independence in older adults. Aging Research Reviews. 24(Pt B): 304-27.

Woods AJ, Cohen RA, Pahor M.  2013. Cognitive Frailty: Frontiers and Challenges. Journal of Nutrition, Health, and Aging. 17(9): 741-743.

Woods AJ, Goksun T, Chatterjee A, Zelonis S, Mehet A, Smith S.  2013. The development of organized visual search. Acta Psychologica.143(2): 191-199.

Goksun T, Woods AJ, Chatterjee A, Zelonis S, Glass L, Smith SE.  2013. Elementary school children’s attentional biases in physical and numerical space. European Journal of Developmental Psychology.10(4): 433-448.

Woods AJ, Mark VW, Pitts A, Mennemeier M. 2011. Pervasive cognitive impairment in acute rehabilitation patients “without” brain injury. PM & R: the journal of injury, function, and rehabilitation.3(5): 426-432.

Mark VW, Woods AJ, Mennemeier M, Abbas S, Taub E.  2006. Cognitive assessment for CI therapy in the outpatient clinic. Neurorehabilitation. 21(2): 139-146.

Woods AJ, Mennemeier M, Garcia-Rill E, Meythaler J, Mark VW, Jewell GR, Murphy H.  2006. Bias in magnitude estimation following left hemisphere injury.  Neuropsychologia. 44(8): 1406-1412.

Taylor-Cooke PA, Ricci R, Banos JH, Zhou X, Woods AJ, Mennemeier MS.  2006. Perception of motor strength and stimulus magnitude are correlated in stroke patients. Neurology. 66(9): 1444-1446.

Mennemeier M, Pierce C, Dowler R, Chatterjee A, Anderson B, Jewell G, Woods AJ, Mark VW.  2005. Biases in attentional orientation and magnitude estimation explain crossover: neglect is a disorder of both. Journal of Cognitive Neuroscience. 17(18): 1194-1211.

Mark VW, Oberhue AM, Henderson C, Woods AJ.  2005. Ballism after stroke responds to standard physical therapeutic interventions. Archives of Physical Medicine and Rehabilitation. 86(6): 1226-1233.

Mark VW, Woods AJ, Ball KK, Roth DL, Mennemeier M.  2004. Disorganized search is not a consequence of neglect. Neurology. 63(1): 78-84. 

Aging & Depression

O’Shea D, Dotson V, Woods AJ, Porges E, Williamson J, O’Shea A, Cohen R. 2018. Depressive symptom dimensions and their association with hippocampal and entorhinal cortex volumes in community dwelling older adults. Frontiers in Aging Neuroscience. 10:40. 

Szymkowicz SM, Woods AJ, Dotson V, Porges EC, Nissim N, O’Shea A, Cohen R, Ebner N. Associations between subclinical depressive symptoms and reduced brain volume in middle-aged to older adults. Aging and Mental Health.1-10. Accepted January 2017

Szymkowicz SM, McLaren ME, O’Shea A, Woods AJ, Anton S, Dotson V. 2017. Depressive symptoms modify age effects on hippocampal subfields. Geriatrics and Gerontology International. 17(10): 1494-1500

McLaren ME, Szymkowicz SM, O’Shea A, Woods AJ, Anton S, Dotson VM.2016. Vertex-wise Examination of Symptom Dimensions of Subthreshold Depression and Brain Volumes. Psychiatry Research: Neuroimaging. 260: 70-75.

Szymkowicz SM, McLaren ME, Kirton JW, O’Shea A, Woods AJ, Manini TM, Anton SD, Dotson VM. 2016. Depressive symptom severity is associated with increased cortical thickness in older adults. International Journal of Geriatric Psychiatry. 31(4): 325-333.

McLaren ME, Szymkowicz SM, O’Shea A, Woods AJ, Anton SD, Manini TM, Dotson VM.  2016. Dimensions of depressive symptoms and cingulate volumes in older adults. Translational Psychiatry. 6(4):e788.

Cognition & Perception: General

Kranjec A, Lehet M, Woods AJ, Chatterjee A. Time is not more abstract than space in sound. Frontiers in Psychology. Accepted January 2019. 

White TL, Monnig MA, Walsh EG, Nitenson AZ, Harris AD, Cohen RA, Porges EC, Woods AJ, Lamb D, Boyd C, Fekir S. 2018. Psychostimulant drug effects on glutamate, Glx, and creatine in the anterior cingulate cortex and subjective response in healthy humans. Neuropsychopharmacology.43(7): 1498-1509.

Piedimonte A, Woods AJ, Chatterjee A. 2015. Disambiguating ambiguous motion perception: what are the cues? Frontiers in Psychology. 6: 902.

Woods AJ, Kranjec A, Lehet M, Chatterjee A. 2015. Expertise and decision-making in American football. Frontiers in Psychology.6: 994.

Yamamoto N, Philbeck JW, Woods AJ, Gajewski D, Chichka D, Potollichio S, Caputy A.  2014. Medial temporal lobe role for trajectory prediction in human path integration. PLoS ONE. 9(5): e96583.

Woods AJ, Lehet M, Chatterjee A. 2012. Context modulates the contribution of time and space in causal inference. Frontiers in Psychology.3: 371. J

Amorapanth P, Kranjec A, Bromberger B, Lehet M, Widick P, Woods AJ, Kimberg DY, Chatterjee A. 2012. Language, perception, and the schematic representation of spatial relations. Brain & Language. 120(3): 226-236.

Philbeck JW, Woods AJ, Kontra C, Zdenkova P. 2010. A comparison of blindpulling to blindwalking as measures of perceived absolute distance. Behavioral Research Methods. 42(1): 148-160.

Woods AJ, Philbeck JW, Danoff J. 2009. The various “perceptions” of distance: an alternative view of how effort affects distance judgments. Journal of Experimental Psychology: Human Perception & Performance. 35(4): 1104-1117.

Philbeck JW, Woods AJ, Arthur J, Todd J.  2008. Progressive locomotor recalibration during blind walking. Attention, Perception & Psychophysics. 70(8): 1459-1470.

Woods AJ, Mark VW. 2007. Convergent validity of executive organization measures on cancellation. Journal of Clinical and Experimental Neuropsychology. 29(7): 719-723.

 

Books, Edited

Knotkova H, Bikson M, Nitsche M, Woods AJ.Practical Guide to Transcranial Direct Current Stimulation.Springer New York, in post-production May 2018. November 2018 print date.

 

Books, Contributor of Chapter(s)

Jaberzadeh S, Martin D, Knotkova H, Woods AJ.Methodological considerations for selection of tDCS approach, protocol and device. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Woods AJ,Bikson M. Electrodes – preparation, placement, methods for electrode-position determination. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Woods AJ,Bikson M, Chelette KC, Dutta N, Gebodji N, Stagg C. tDCS integration with MRI, EEG, and fNIRS. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Hamilton R, Fregni F, Kessler S, Loo C, Martin D, Knotkova H, Woods AJ.Methodological considerations for tDCS in clinical trials. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Antal A, Woods AJ, Knotkova H. tDCS ethics and professional conduct. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Hampstead B, Woods AJ, Nitsche M. tDCS for functional enhancement and symptom control in neurodegenerative diseases. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Woods AJ, Flöel A, Antonenko D, Hummel F, Knotkova H, Hampstead B. tDCS in aging. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Hamilton R, Shah P, Nitsche M, Woods AJ.tDCS in cognitive neuroscience. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J., (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Nitsche M, Knotkova H, Bikson M, Woods AJ.Challenges, open questions and future direction in tDCS research and applications. Knotkova, H., Bikson, M., Nitsche, M., Woods, A.J. (eds.). Practical Guide to Transcranial Direct Current Stimulation (tDCS): Principles, Procedures and Applications.Springer Publishing. In press.

Nissim N,Woods AJ.Mach Bands. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Ochoa C,Woods AJ.Visual Search. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Szymkowicz SM,Woods AJ.Binocular Disparity. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Szymkowicz SM,Woods AJ.Edge Detection. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Nissim N, Woods AJ.Digit Vigilance Test (DVT). Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Nissim N,Woods AJ.Visual Psychophysics. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

McLaren M,Woods AJ.The Brief Test of Attention. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Sinha P,Bowers D,Woods AJ.D2 Test of Attention. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Nuthi M, Suryadevara U,Woods AJ.Motion Perception. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Suryadevara U,Woods AJ.Motion Parallax. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Suryadevara U,Woods AJ.Eye Dominance. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

O’Shea A,Woods AJ.Useful Field of View. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Hromas LG,Woods AJ.Visual Convergence. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Richards L,Woods AJ.Posterior Cortical Atrophy. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Polejaeva E,Woods AJ.Behavioral Inattention Test (BIT). Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Polejaeva E,Woods AJ.Auditory Selective Attention Test. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

O’Shea D,Woods AJ.Tests of Variables of Attention. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Seider T, Cohen R, Woods AJ. Apperceptive Agnosia. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Seider T, Cohen R, Woods AJ. Visual Assessment Battery. Encyclopedia of Clinical Neuropsychology, 2nd Ed. Springer New York, in press.

Woods AJ, Cohen RA, Pahor M. Cognitive frailty: frontiers and challenges. Vellas, B (eds). White Book on Frailty. International Association on Gerontology and Geriatrics, 2016, pp. 44-47.

Woods AJ, Martin D. Clinical Research and Methodological Aspects for tDCS Research. In Brunoni A, Nitsche M, Loo C. (Eds.) Transcranial Direct Current Stimulation in Neuropsychiatric Disorders: Clinical Principles and Management, Springer, New York, 2016, pp. 393-404. Citations: 3

Non-refereed Publications

Knotkova H, Woods AJ, Bikson M, and Nitsche M.  2015. Transcranial Direct Current Stimulation (tDCS): What Pain Practitioners Need to Know.  Practical Pain Management.  15(3): 58-66. http://www.practicalpainmanagement.com/treatments/interventional/stimulators/transcranial-direct-current-stimulation-tdcs-what-pain

Grants

Principal Investigator

NIA R01AG054077 (Woods/Cohen/Marsiske; MPIs) 09/01/16-04/31/21
National Institutes of Health                                                    $5,778,764
Augmenting Cognitive Training in Older Adults (ACT)
This study is a Phase III definitive multi-site randomized clinical trial with an adaptive design that will establish the benefit of delivering adjunctive transcranial direct current stimulation (tDCS) with cognitive training in older adults to combat cognitive aging. This trial measures both trial success and intervention mechanisms using multimodal neuroimaging and magnetic resonance spectroscopy, as well as comprehensive neurocognitive and functional assessment.
Role: MPI

NIA K01AG050707-A1 (Woods; PI)   09/30/16-05/31/21
National Institutes of Health                                                   $612,715
Neuromodulation of Cognition in Older Adults
The goal of this study will be to investigate the ability of transcranial direct current stimulation to enhance the effectiveness of cognitive training targeting attention, speed of processing, and working memory function in older adults. Training will focus on cognitive aging interventions and advanced magnetic resonance imaging and spectroscopy methods.
Role: PI

NIA U01AG062368 (Edwards; PI)     09/30/18-05/31/20                               $614,914
National Institutes of Health
Planning an adaptive clinical trial of cognitive training to improve function and delay dementia
This two-year U01 project will develop the infrastructure for a large Phase II/III clinical trial investigating the impact of various forms of cognitive training on functional abilities and dementia conversation in patients with mild cognitive impairment. I will lead the UF site on this trial and will also lead the neuroimaging and data management for the pilot trial and in the subsequent full trial submission. This grant involves sites at University of South Florida (parent site), University of California San Francisco and the University of Florida.
Role: Site PI

NIMH R21MH112206 (Woods/Ding, MPIs) 1/15/18-/12/31/19
National Institutes of Health                                                    $395,034
Stimulating Theta Oscillations to Enhance Working Memory
This project will the impact of transcranial alternating current stimulation (tACS) on working memory network synchrony in the theta band of EEG using electrophysiology and functional magnetic resonance imaging.
Role: MPI

Industry Sponsored Trial (Woods; PI) 06/15/16-06/15/18
Osato Research Institute                                                     $268,360
Impact of Fermented Papaya Product on brain energetics, neuroplasticity, and cognition
The goal of this study is to perform a pilot clinical trial investigating the influence of Fermented Papaya Product on brain energetics, neuroplasticity, and cognition in older adults with elevated systemic inflammation using multimodal neuroimaging (fMRI, DWI) and spectroscopy (31P, 1H-MRS), as well as assessment of systemic inflammation and cognition.
Role: PI

McKnight Brain Research Foundation(Woods/Bowers, MPIs)  05/1/18-04/31/20
McKnight Brain Research Foundation                                              $120,000
CAM-CTRP Pilot Study: Near infrared brain stimulation in older adults.
The goal of this funding is to use near infrared brain stimulation to improve cognition, 31P MRS markers of ATP, and functional neuroimaging biomarkers of cognitive and metabolic decline in healthy aging in a 2 site phase II pilot trial.
Role: MPI

McKnight Brain Research Foundation(Woods; PI)   07/1/15-07/1/19
McKnight Brain Research Foundation                                             $114,164
CAM-CTRP Pilot Study: Neuromodulation of cognition in older adults: The stimulated brain study
The goal of this funding is to use transcranial direct current stimulation to improve functional neuroimaging biomarkers of cognitive and metabolic decline in healthy aging.
Role: PI

Co-Principal Investigator

UF Pain and Aging Pilot Initiative (Woods/Cruz-Almeida, Co-PIs)
University of Florida                                                         $30,000
Treating generalized pain in older adults with transcranial direct current stimulation (tDCS)
This study will use two weeks of tDCS to treat generalized pain disorder in older adults and investigate neural correlates of tDCS related analgesic effects.
Role: Co-PI

Co-Investigator

NIA R37AG033906 (Fillingim; PI) 05/01/19-04/31/24
National Institutes of Health                                              $6,144,138
Understanding Pain and Limitations in Osteoarthritic Disease
The goal of this project is to evaluate transcranial direct current stimulation and mindfulness based stress reduction, alone and in combination, as treatments of chronic osteoarthritic knee pain in a two site phase II clinical trial.
Role: Co-I

NIMHRF1MH114290-01 (Sadlier; PI) 07/19/17-07/18/21
National Institutes of Health                                              $2,046,092
Mechanism and dosimetry exploration in transcranial electrical stimulation using magnetic resonance current mapping methods
The goal of this project is to pioneer an objective measure of current flow in the brain using state of the art magnetic resonance imaging methods combined with in scanner application of tDCS and tACS. This project will also assess the relationship between activation in working memory related regions from an NBACK fMRI task and correspondence of change following F3-F4 in scanner tDCS.
Role: Co-I

NIA R21AG053736-01A1(Clark; PI)07/01/17-06/31/19
National Institutes of Health                                               $189,233
Combining tDCS and neurorehabilitation to treat age-related deficits of mobility and cognition
The goal of this study is to obtain pilot data for a full-scale clinical trial combining transcranial direct current stimulation (tDCS) and complex walking intervention to enhance mobility in older adults.
Role: Co-I (overlap covered by K01)

UF Cancer and Aging Initiative (Lyon/Cohen, Co-PIs)
University of Florida                                                      $100,000
Neuroinflammation and Cognitive Dysfunction in Older Women with Breast Cancer
This pilot study will investigate the influence of chemotherapy on cognitive and brain function, focusing on the role of neuroinflammation in chemotherapy-associated cognitive decline.
Role: Co-I(Neuroimaging expertise/analyses) (Effort reduced to 0% as of 9/30 due to K01AG050707-A1)

Mentorship-Based Funding

NIA T32 (McLaren: Student PI)                                  04/01/17-03/30/19
National Institutes of Health                                              $80,000
Dissociating anhedonia and apathy in older adults: an fMRI study
The goal of this project is for the student to obtain training in functional magnetic resonance imaging on a project that enrolls older adults with symptoms of anhedonia and apathy and undergoing an fMRI EEFRT task, in addition to testing for cognitive function and depression.
Role: Mentor

TL1 (Nissim; Student PI)                                            08/01/16-07/30/18
National Institutes of Health/UF CTSI                                     $80,000
Enhancing working memory through neuromodulation and cognitive training
The goal of this project is for the student to obtain training in clinical translational science on a project using tDCS and cognitive training to enhance cognitive and functional brain response in older adults.
Role: Mentor

NIAAA F31AA024060 (Bryant; Student PI)               05/01/15-04/30/18
National Institutes of Health                                             $109,474
Working memory: a critical factor underlying alcohol reduction intervention response
The goal of this project is to evaluate the role of working memory function in response to an effective alcohol reduction intervention (Motivational Interviewing) in HIV and non-HIV older adults. The student will receive training in functional and structural magnetic resonance imaging methods.
Role: Co-Mentor

Consultant

NIH R01AG058724, 09/01/18 to 08/31/24, Treating mild cognitive impairment using high definition transcranial direct current stimulation. Dr. Woods serves as an expert consultant for the tDCS and neuroimaging aims of the aforementioned R01 awarded to Dr. Benjamin Hampstead at University of Michigan.

Supplement to NIH R01MH111896, 06/01/18 to 08/31/19, A toolbox to control and enhance tDCS spatial precision. Dr. Woods serves as an expert consultant for the aging, tDCS, and neuroimaging aims of the awarded one-year supplement to the aforementioned R01 awarded to Dr. Marom Bikson at City College of New York.

YB-STPS1801, A pilot study of home-delivered non-invasive neurostimulation to evaluate improvement in mood and symptom distress in the elderly. Dr. Woods serves as an expert consultant for the aging and tDCS aims of this project awarded to Dr. Helena Knotkova at the Metropolitan Jewish Health System Institute for Innovations in Palliative Care in New York.

Other Support

L30 AG051178 (Woods; PI)                                       07/01/15-06/31/19
NIH Loan Repayment Program; National Institute on Aging (NIA)
Study Title: Neuromodulation of Cognition in Older adults
Two-year loan repayment support for research on the use of transcranial direct current stimulation paired with cognitive training to enhance cognitive function in older adults.
Role: PI

Professional Membership

Society for Neuroscience

World Academy of Art and Science

Association for Psychological Science

American Psychological Association

APA Division 20: Adult Development and Aging

North American Neuromodulation Society

International Neuropsychological Society

International Neuromodulation Society