Neuroimaging

The Woods Lab uses multimodal neuroimaging to investigate neural mechanisms underlying intervention effects, as intervention outcome measures, and to investigate brain-based variables with predictive value for individual differences in intervention response. The lab has expertise in structural (T1/MPRAGE, T2, FLAIR), diffusion weighted imaging (DWI), task-based and resting state functional magnetic resonance imaging (fMRI), proton magnetic resonance spectroscopy (1H-MRS), and phosphorus (31P) MRS. These imaging modalities are central to studies carried out in the lab. The lab has access to two research dedicated 3T MRI systems in the McKnight Brain Institute Advanced Magnetic Resonance Imaging and Spectroscopy (AMRIS) facility РSiemens Prisma and Philips Achieva. The labs behavior testing space and neuromodulation facilities are located adjacent to both scanners. The lab is equipped with dedicated stimulus delivery computers for each scanner and a variety of task-based functional imaging paradigms using EPRIME. The lab also maintains assess to a whole head dual tuned 31P MRS coil on the Philips system to assess markers of mitochondrial function (alpha-, beta-, & gamma-ATP) as well as other markers of energy metabolism.  In addition, the lab uses the UF HiperGator super-computer for image processing and analyses. This computer infrastructure provides high-throughput parallelized processing of imaging data using FreeSurfer, SPM, FSL, AFNI, and other local processing software.  Working with High Performance Computing at the University of Florida, we have created a state-of-the-art semi-automated imaging pipeline for rapid processing of large imaging datasets, as well as a variety of automated quality control reporting mechanisms.

imaging